Active Ingredient/Content
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Efficacy/Indication
- Treatment of complicated urinary tract infections (UTI), uncomplicated skin and skin structure infections (SSSI), acute bacterial exacerbation of chronic bronchitis(ABECB), community-acquired pneumonia (CAP), acute uncomplicated urethral and cervical gonorrhea, nongonococcal urethritis and cervicitis, mixed infections of urethra and cervix, acute pelvic inflammatory disease (PID), uncomplicated cystitis, and prostatitis caused by susceptible strains of microorganisms.
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Administration/Dosage
- Adults:
- ABECB/CAP/SSSI: 400mg q12h for 10 days. Cervicitis/Urethritis: 300mg q12h for 7 days. Gonorrhea: 400mg single dose. PID: 400mg q12h for 10-14 days.
- Uncomplicated Cystitis: 200mg q12h for 3 days (Escherichia coli or Klebsiella pneumoniae) or 7 days (other pathogens). Complicated UTI: 200mg q12h for 10 days.
- Prostatitis:(E. coli) 300mg q12h for 6 weeks.
- CrCl 20-50mL/min: After regular initial dose, give q24h.
- CrCl <20mL/min: After regular initial dose, give 50% of normal dose q24h. Severe Hepatic Impairment: Max: 400mg/day.
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